Custom Aptamers

Custom aptamer identification:

NeoVentures provides the most advanced and comprehensive aptamer development service available (RNA or DNA, modified or natural nucleotides).

We provide the following:
 

- Design of a customized selection strategy for your target.
- Delivery of at least two manual selections per target, with appropriate adjustments for stringency and counter-selection in every selection round.
- Delivery includes use of our proprietary FRELEX platform
- Next generation sequence analysis of libraries from relevant selection rounds
- Identification of candidate sequences with proprietary Neo-aptamer NGS analysis software, based on abundance and enrichment rates of millions of   
  sequences.
- High throughput binding assays
- Full technical support for client applications
 


                     NeoVentures advantages:

 

- Our services make good business and scientific sense for our clients.
- We share with you all the sequences we characterize.
- We grant clients a royalty free, exclusive, global license to the use of all sequences as applied to their target. 
- Next generation sequencing provides clients with broad IP protection on their investment.
- We work with clients to ensure that our binding assays with candidate aptamers mimic proposed application conditions. 
- We work with small metabolites, peptides, proteins, cell lines, and tissues.
- We will perform counter-selection with appropriate similar targets as well as matrices such as blood serum or urine.
 

- Our aptamers are commercial ready


- Access to state of the art thinking and technology:
- Mathematical models of aptamer selection process
- Proprietary FRELEX technology for selection
- Proprietary analysis of next generation sequencing results.
- Proprietary high throughput binding assay platforms-
- Experience handing off successful results to clients.
- Experience with the immobilization of small molecules
- Capacity to work with cells and tissues


Our base price for a natural nucleotide DNA project is US$35,000. Payment terms are US$20,000 prior to project initiation, US$15,000 payable upon our delivery of aptamer sequences that meet agreed upon criteria. Base price is US$50,000 for modified nucleotides or RNA projects.


We are open to discussing your project with you extensively before you make a commitment to proceed. Please contact us at info@neoventures.ca


We reserve the right to decline a proposed project based on our assessment of the probability of success with the target molecule.