Our Services

Aptamer Selection

FRELEX: Free-Free aptamer selection method

Contrasting channels in a selection strategy

Mathematical analysis

NGS Analysis

Preparation of up to 12 selected libraries for sequencing analysis

Next generation sequencing on an Illumina HiSeq 2500

Analysis of copy number with our proprietary software

Binding Assays

Synthesis of up to ten candidate sequences

Surface plasmon resonance imaging (SPRi)

Isothermal titration calorimetry (ITC)

Analysis of binding curves

Generation of ka, kd and kD values for each candidate sequence

Binding Affinity Simulator

To help diagnostic developers understand whether an aptamer will work for their application we are providing an online binding affinity simulator. The simulator will provide you with the amount of target that the aptamer will bind at equilibrium.

Latest News

Penner et al. Blood-based diagnostics of Alzheimer’s disease. Review paper.

Abstract: This review is focused on the methods used for biomarker discovery for Alzheimer’s disease (AD) in blood rather than […]

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Development of novel aptamers for low-density lipoprotein particle quantification

Abstract: Cardiovascular disease (CVD) remains the leading cause of death worldwide. Low-density lipoprotein cholesterol (LDL-C) is commonly used for CVD […]

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Aptamers as biomarkers for neurological disorders.

Abstract : The act of selecting aptamers against blood serum leads to deep libraries of oligonucleotide sequences that bind to […]

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Projects
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info@neoventures.ca

5 York Street, Unit # 3
London, Ontario, N6A 1A1
Canada

Phone: 1 519 601 7511